Aging and Its Impact on Anesthesia: A Focus on Physiological and Pharmacological Change
The aging process brings profound physiological changes that significantly impact the pharmacokinetics and pharmacodynamics of drugs used in anesthesia. Alterations in body composition, organ function, and receptor sensitivity can affect drug distribution, metabolism, and clearance, making older adults more vulnerable to adverse effects. For anesthesiologists, understanding these changes is crucial for tailoring anesthesia care to … Read more