Clinical Applications: Handling Air Bubbles: In medical settings, understanding Archimedes’ principle is crucial. For instance, if there’s an air bubble in a syringe, keeping the syringe’s cone pointed downward prevents injecting air into a patient. Open-Heart Surgery: During cardiac surgeries, de-airing is vital to prevent air bubbles from reaching the brain and causing issues. Anesthesiologists … Read more
John B. Glen spent 13 years perfecting propofol; for his efforts, he was recently honoured with the 2018 Lasker Award for clinical research. Propofol, in a form solubilized in cremophor EL, was first identified as a drug candidate in 1973 and began clinical trials in 1977.Cremophor caused anaphylactic reactions, so this formulation was taken off … Read more
Background and Experiments with Nitrous Oxide: Thomas Beddoes established the Pneumatic Institution in Bristol, England, to explore the therapeutic use of various gases, including nitrous oxide, in treating pulmonary tuberculosis. Humphry Davy, a young chemist, was recruited to oversee the laboratory at the institution. He conducted experiments with nitrous oxide, exploring its effects on himself … Read more
