Magnesium Sulphate: Clinical Uses, Pharmacology, Physiology, and Toxicity

IntroductionMagnesium sulphate (MgSO4) is a versatile compound with wide-ranging clinical applications due to its physiological importance. In this article, we will explore its clinical uses, basic pharmacology, physiology, and potential toxicity. Clinical Uses Clinical Condition Mechanism of Action Pre-eclampsia and Eclampsia Reduces systemic vascular resistance, CNS excitability. Tocolysis Induces uterine relaxation. Acute Arrhythmias Effective in … Read more

Understanding and Modulating the Perioperative Stress Response in Surgery

Surgery is a significant physiological stressor that triggers a complex response in the body. This stress response can be categorized into two main components: the neuroendocrine-metabolic response and the inflammatory-immune response. The extent and impact of this response depend on various factors, including the type and invasiveness of the surgical procedure. Categories of Stress Response … Read more

Anesthesia’s Evolution: From Ether Day to John Snow’s Precision

Year Events and Developments 1846 – October 16, 1846: William T.G. Morton’s successful demonstration of ether anesthesia in Boston became known as “Ether Day.” – December 16, 1846: A successful trial of ether anesthesia took place in Paris. – December 19, 1846: Anesthesia was administered in both Scotland and London, with one case in London … Read more

Anaesthetic Challenges in preterm babies

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