Index Information Overview – Ketamine is a phencyclidine derivative that induces dissociative anesthesia. – It affects EEG by dissociating thalamocortical and limbic systems. – Hypertonus and muscle movements may occur independently of surgical stimulation. – Ketamine induces amnesia and intense analgesia. – Emergence delirium limits its clinical use. Structure Activity Relationship – Ketamine has two … Read more
The field of neuroanesthesia has witnessed significant advancements in the past two decades, aligning itself with the rapid technological developments in neurosurgery. These advancements have paved the way for novel surgical approaches and procedures, which, in turn, have introduced new challenges in the perioperative care of neurosurgical patients. Notably, the aging population, characterized by an … Read more
Introduction Deep Brain Stimulation (DBS) is a revolutionary neurosurgical procedure that has transformed the treatment landscape for various neurological disorders. This comprehensive guide delves into the intricacies of DBS surgery, covering patient selection, surgical technique, anesthetic management, and the management of perioperative complications. Patient Selection for DBS Multidisciplinary Approach: The journey begins with a multidisciplinary … Read more
Overview Introduction Aspect Information Diverse Origins Various neoplasms from different CNS cells Prevalence 80% of adult brain tumors, 40% in children Incidence 23.03 per 100,000 population annually Common Types Glioblastomas (47.7%), Meningiomas (53.1%) Cerebral Metastases 30% in systemic cancer patients Metastatic Sources Lung, breast, melanoma, renal, colorectal Classification WHO categorizes based on histology, genes Etiology … Read more
There was a publication called “The Zoist: A Journal of Cerebral Physiology and Mesmerism, and Their Applications to Human Welfare” that ran from April 1843 until December 1855. Initiated by a 19th-century doctor who also dabbled in hypnotism (or mesmerism), John Elliotson. Important to the development of anaesthesia, this publication chronicled the use of mesmerism … Read more
Anaesthesia journals have been published since the early 1920s, although until recently it was widely thought that this was when they were initially published. Among them were the “Current Researches in Anaesthesia and Analgesia,” which first appeared in August 1922, and the “British Journal of Anaesthesia,” which first appeared in 1923–1924. It was eventually established, … Read more
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Introduction: In the realm of anesthesia, understanding the relationship between aging and Minimal Alveolar Concentration (MAC) of inhalational agents is pivotal. MAC represents the minimum concentration of an inhalational anesthetic required to prevent movement in 50% of patients following surgical incision. This article delves into the intricate interplay between aging and MAC, shedding light on how … Read more
Introduction: Pharmacokinetics: PULMONARY SYSTEM: The aging pulmonary system can influence the behavior of inhalational anesthetic agents in several ways: CARDIOVASCULAR SYSTEM 7. Effect on Inhalational Agents: 8. Choice of Inhalational Agents: 9. Cardiac Depression and Contractility: 10. Induction and Emergence: BODY COMPOSITION: 1. Increase in Body Fat Percentage: 2. Loss of Skeletal Muscle Mass: 3. … Read more
Introduction: Causes: Pathophysiology: Prevalence and Common Patterns: Medications and Other Influences: Unique Variations in Special Populations: Treatment / Management: Differential Diagnosis: Prognosis: Complications: Managing the Impact of Anesthesia and Surgery Anesthesia and surgery can potentially worsen existing Sick Euthyroid Syndrome (SES) or Non-Thyroidal Illness Syndrome (NTIS) in some patients, although it primarily depends on various … Read more
