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Research

Efficacy of Bisoprolol premedication in controlling bloodloss during functional endoscopic sinus surgery

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BACKGROUNDFunctional endoscopic sinus surgery (FESS) is well accepted as surgical  treatment of sinusitis and nasal polyps. The success of this procedure depends on the visual clarity of the highly vascular surgical field through the endoscope. Various drugs and anaesthetic techniques have been tried in an effort to provide the appropriate surgical conditions for FESS. The purpose … Read more

The effect of intravenous low dose magnesium sulphate on early postoperative pain after laparoscopic cholecystectomy.

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Background: The concept of preemptive analgesia was introduced by C. J. Woolf et al. Magnesium Sulphate, an antagonist of N-methyl-D-aspartate (NMDA) receptors and its associated channels causes modulation of acute pain reducing postsurgical pain intensity and dosage of analgesics. Our study was done to evaluate the postoperative analgesic efficacy of single low dose magnesium sulphate … Read more

A comparative study of two supraglottic airway devices the i-gel® and LMA supreme TM in reducing the incidence of post operative sore throat in patients undergoing day care surgeries under general anesthesia

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Postoperative sore throat is a common complaint after general anaesthesia. Airway trauma caused by laryngoscopy and endotracheal intubation are mainly responsible for this. Supraglottic airway devices offer an alternative to traditional tracheal intubation with potential benefit for ease of fit, less disturbance of the airway and less incidence of postoperative sore throat. The aim of … Read more

Comparison of safety and efficacy of Ramosetron and Ondansetron for post-operative nausea and vomiting in Laparoscopic Cholecystectomy

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Introduction:Post-operative nausea and vomiting (PONV) is a common complication after anesthesia and surgery, leading to distress and potential complications. Ramosetron, a newer 5-HT3 receptor antagonist, has shown to have more potent and longer-lasting antiemetic effects compared to first-generation 5-HT3 receptor antagonists like ondansetron. This study aimed to compare the efficacy of ramosetron and ondansetron for … Read more

A Comparative Study of Haemodynamic Effects and Early Recovery Profile of Desflurane and Sevoflurane in Patients Undergoing Modified Radical Mastectomy under General Anaesthesia

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Introduction:Inhaled general anesthetics play a crucial role in balanced anesthesia, with haemodynamic stability and early recovery being essential aspects of an effective anesthetic technique. Desflurane and sevoflurane are two recently developed inhaled anesthetics widely used for maintaining anesthesia. This study aims to observe and compare the haemodynamic effects and early recovery profiles of desflurane and … Read more

The Effect of Warmed Irrigation Fluid on Core Body Temperature in Patients Undergoing Transurethral Resection of the Prostate under Spinal Anaesthesia

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Introduction:Mammals and birds are homeothermic, maintaining a nearly constant internal body temperature. However, anaesthetic-induced inhibition of thermoregulation, combined with exposure to a cold operating room environment, can lead to postoperative hypothermia in unwarmed patients. Hypothermia is particularly concerning after Transurethral Resection of the Prostate (TURP) surgery, as it is strongly correlated with cardiovascular risk factors, … Read more

Observational Study: Awareness in Thoracolumbar Spine Surgeries with Neurophysiological Monitoring

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Spine surgeries with neurophysiological monitoring is one of the most challenging surgery in view of anaesthesia. The Evoked Potential Monitors SSEP and MEP, though facilitates early detection of any intraoperative neuronal injuries is easily influenced by anaesthetic drugs and inhalational agents. Hence the anaesthetic technique has to be modified reducing the dose of inhalational agents … Read more

Correlation between central venous pressure in patients undergoing spine surgery in prone position

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Background:Patients undergoing major spine surgeries are at risk of significant blood loss and hemodynamic disturbances, necessitating intraoperative monitoring of central venous pressure (CVP) to guide fluid therapy. However, CVP monitoring via central venous cannulation carries its own risks and discomfort. Peripheral venous pressure (PVP) monitoring through a peripheral intravenous catheter has been proposed as an … Read more

EMERGING CIRCUITS IN MESOLIMBIC SYSTEM

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Introduction to Anesthesia and Circuitry:Anesthesia is a medical practice that involves administering medications to induce a state of unconsciousness or sedation, allowing for surgical procedures to be performed without pain or awareness. Understanding the neural circuits involved in anesthesia is crucial for optimizing patient care and outcomes. Neural Pathways and Anesthesia:The human brain consists of … Read more

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